Where Should I Start?

Simple GLP Starting Guide

Start here and follow the path that fits you best.

Step 1: Have You Used GLP-Based Peptides Before?

→ No, I’m brand new

Start low and let your body adjust.

Best starting options:

• Semaglutide → 0.25 mg weekly

• Tirzepatide → 2.5 mg weekly

• Retatrutide → 1 mg weekly

👉 Stay here for 4 weeks before increasing

→ Yes, I’ve used Semaglutide before

If you tolerated it well:

• Move to 0.5 mg – 1 mg weekly

If you had side effects:

• Restart at 0.25 mg weekly

→ Yes, I’ve used Tirzepatide before

If restarting after time off:

• Go back to 2.5 mg weekly

If currently active and stable:

• Continue your current dose or increase gradually:

  • 5 mg → 7.5 mg → 10 mg

→ I want stronger appetite control / faster results

This is where most people jump too fast.

Better approach:

• Start with Tirzepatide (2.5 mg)

• Or progress Semaglutide to 1 mg+

👉 Don’t skip steps, that’s where side effects show up

→ I want the most advanced option

• Retatrutide is the newest and strongest of the three

• Still start at 1 mg weekly

👉 This is not something you jump into at a high dose

Step 2: What’s Your Goal?

Fat loss with the least side effects

→ Start with Semaglutide

Strong appetite suppression + steady fat loss

→ Go with Tirzepatide

Maximum fat loss potential (advanced users)

→ Consider Retatrutide

Step 3: When Do You Increase?

Simple rule:

• Stay at each dose for at least 4 weeks

• Increase only if:

  • Hunger is returning

  • Progress has slowed

  • Side effects are minimal

The Biggest Mistake to Avoid

Starting too high.

That’s what leads to:

• nausea

• fatigue

• quitting early

The people who get the best results are the ones who:

• start low

• stay consistent

• increase gradually

Simple Starting Summary

• New → Start low (Semaglutide 0.25 / Tirzepatide 2.5 / Retatrutide 1)

• Experienced → Resume or step up carefully

• Advanced → Retatrutide, but still titrate